Učitavanje...
CpG domains downstream of TSSs promote high levels of gene expression
CpG dinucleotides are known to play a crucial role in regulatory domains, affecting gene expression in their natural context. Here, we demonstrate that intragenic CpG frequency and distribution impacts transgene and genomic gene expression levels in mammalian cells. As shown for the Macrophage Infla...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3973331/ https://ncbi.nlm.nih.gov/pubmed/24413563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1358 |
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