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DNA methylation in human epigenomes depends on local topology of CpG sites

In vertebrates, methylation of cytosine at CpG sequences is implicated in stable and heritable patterns of gene expression. The classical model for inheritance, in which individual CpG sites are independent, provides no explanation for the observed non-random patterns of methylation. We first invest...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Lövkvist, Cecilia, Dodd, Ian B., Sneppen, Kim, Haerter, Jan O.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914085/
https://ncbi.nlm.nih.gov/pubmed/26932361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw124
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