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DNA methylation in human epigenomes depends on local topology of CpG sites

In vertebrates, methylation of cytosine at CpG sequences is implicated in stable and heritable patterns of gene expression. The classical model for inheritance, in which individual CpG sites are independent, provides no explanation for the observed non-random patterns of methylation. We first invest...

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Publicat a:Nucleic Acids Res
Autors principals: Lövkvist, Cecilia, Dodd, Ian B., Sneppen, Kim, Haerter, Jan O.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914085/
https://ncbi.nlm.nih.gov/pubmed/26932361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw124
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