Effects of non-CpG site methylation on DNA thermal stability: a fluorescence study

Cytosine methylation is a widespread epigenetic regulation mechanism. In healthy mature cells, methylation occurs at CpG dinucleotides within promoters, where it primarily silences gene expression by modifying the binding affinity of transcription factors to the promoters. Conversely, a recent study...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Nardo, Luca, Lamperti, Marco, Salerno, Domenico, Cassina, Valeria, Missana, Natalia, Bondani, Maria, Tempestini, Alessia, Mantegazza, Francesco
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2015
Konular:
Gene regulation, Chromatin and Epigenetics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678853/
https://ncbi.nlm.nih.gov/pubmed/26354864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv884
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