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The impact of intragenic CpG content on gene expression

The development of vaccine components or recombinant therapeutics critically depends on sustained expression of the corresponding transgene. This study aimed to determine the contribution of intragenic CpG content to expression efficiency in transiently and stably transfected mammalian cells. Based...

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Autori principali: Bauer, Asli Petra, Leikam, Doris, Krinner, Simone, Notka, Frank, Ludwig, Christine, Längst, Gernot, Wagner, Ralf
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896515/
https://ncbi.nlm.nih.gov/pubmed/20203083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq115
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