The impact of intragenic CpG content on gene expression

The development of vaccine components or recombinant therapeutics critically depends on sustained expression of the corresponding transgene. This study aimed to determine the contribution of intragenic CpG content to expression efficiency in transiently and stably transfected mammalian cells. Based...

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Main Authors: Bauer, Asli Petra, Leikam, Doris, Krinner, Simone, Notka, Frank, Ludwig, Christine, Längst, Gernot, Wagner, Ralf
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2010
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896515/
https://ncbi.nlm.nih.gov/pubmed/20203083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq115
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