טוען...
Checkpoint kinase 1 negatively regulates somatic hypermutation
Immunoglobulin (Ig) diversification by somatic hypermutation in germinal center B cells is instrumental for maturation of the humoral immune response, but also bears the risk of excessive or aberrant genetic changes. Thus, introduction of DNA damage by activation-induced cytidine deaminase as well a...
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| Main Authors: | , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3973322/ https://ncbi.nlm.nih.gov/pubmed/24423870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1378 |
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