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Involvement of Rad18 in somatic hypermutation
Somatic hypermutation of Ig genes is initiated by transcription-coupled cytidine deamination in Ig loci. Error-prone processing of the resultant DNA lesions is thought to cause extensive mutagenesis, but it is presently an enigma how and why error-prone rather than error-free repair pathways are rec...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1567700/ https://ncbi.nlm.nih.gov/pubmed/16873544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605146103 |
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