Loading...
Involvement of Rad18 in somatic hypermutation
Somatic hypermutation of Ig genes is initiated by transcription-coupled cytidine deamination in Ig loci. Error-prone processing of the resultant DNA lesions is thought to cause extensive mutagenesis, but it is presently an enigma how and why error-prone rather than error-free repair pathways are rec...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2006
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1567700/ https://ncbi.nlm.nih.gov/pubmed/16873544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605146103 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|