Checkpoint kinase 2 is required for efficient immunoglobulin diversification

Maintenance of genome integrity relies on multiple DNA repair pathways as well as on checkpoint regulation. Activation of the checkpoint kinases Chk1 and Chk2 by DNA damage triggers cell cycle arrest and improved DNA repair, or apoptosis in case of excessive damage. Chk1 and Chk2 have been reported...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Davari, Kathrin, Frankenberger, Samantha, Schmidt, Angelika, Tomi, Nils-Sebastian, Jungnickel, Berit
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614315/
https://ncbi.nlm.nih.gov/pubmed/25483076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.964112
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