SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome

Aberrant expression of the secreted protein, acidic, cysteine-rich (osteonectin) (SPARC) gene, which encodes a matricellular protein that participates in normal tissue remodeling, is associated with a variety of diseases including cancer, but the contribution of SPARC to malignant growth remains con...

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Detalhes bibliográficos
Main Authors: Alachkar, Houda, Santhanam, Ramasamy, Maharry, Kati, Metzeler, Klaus H., Huang, Xiaomeng, Kohlschmidt, Jessica, Mendler, Jason H., Benito, Juliana M., Hickey, Christopher, Neviani, Paolo, Dorrance, Adrienne M., Anghelina, Mirela, Khalife, Jihane, Tarighat, Somayeh S., Volinia, Stefano, Whitman, Susan P., Paschka, Peter, Hoellerbauer, Pia, Wu, Yue-Zhong, Han, Lina, Bolon, Brad N., Blum, William, Mrózek, Krzysztof, Carroll, Andrew J., Perrotti, Danilo, Andreeff, Michael, Caligiuri, Michael A., Konopleva, Marina, Garzon, Ramiro, Bloomfield, Clara D., Marcucci, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973087/
https://ncbi.nlm.nih.gov/pubmed/24590286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70921
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