RUNX1 Mutations Are Associated With Poor Outcome in Younger and Older Patients With Cytogenetically Normal Acute Myeloid Leukemia and With Distinct Gene and MicroRNA Expression Signatures

PURPOSE: To determine the association of RUNX1 mutations with therapeutic outcome in younger and older patients with primary cytogenetically normal acute myeloid leukemia (CN-AML) and with gene/microRNA expression signatures. PATIENTS AND METHODS: Younger (< 60 years; n = 175) and older (≥ 60 yea...

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Detalhes bibliográficos
Main Authors: Mendler, Jason H., Maharry, Kati, Radmacher, Michael D., Mrózek, Krzysztof, Becker, Heiko, Metzeler, Klaus H., Schwind, Sebastian, Whitman, Susan P., Khalife, Jihane, Kohlschmidt, Jessica, Nicolet, Deedra, Powell, Bayard L., Carter, Thomas H., Wetzler, Meir, Moore, Joseph O., Kolitz, Jonathan E., Baer, Maria R., Carroll, Andrew J., Larson, Richard A., Caligiuri, Michael A., Marcucci, Guido, Bloomfield, Clara D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2012
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732007/
https://ncbi.nlm.nih.gov/pubmed/22753902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2011.40.6652
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