Age-Related Prognostic Impact of Different Types of DNMT3A Mutations in Adults With Primary Cytogenetically Normal Acute Myeloid Leukemia

PURPOSE: To determine the frequency of DNMT3A mutations, their associations with clinical and molecular characteristics and outcome, and the associated gene- and microRNA-expression signatures in primary cytogenetically normal acute myeloid leukemia (CN-AML). PATIENTS AND METHODS: Four hundred fifte...

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Detalhes bibliográficos
Main Authors: Marcucci, Guido, Metzeler, Klaus H., Schwind, Sebastian, Becker, Heiko, Maharry, Kati, Mrózek, Krzysztof, Radmacher, Michael D., Kohlschmidt, Jessica, Nicolet, Deedra, Whitman, Susan P., Wu, Yue-Zhong, Powell, Bayard L., Carter, Thomas H., Kolitz, Jonathan E., Wetzler, Meir, Carroll, Andrew J., Baer, Maria R., Moore, Joseph O., Caligiuri, Michael A., Larson, Richard A., Bloomfield, Clara D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2012
Assuntos:
ORIGINAL REPORTs
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295550/
https://ncbi.nlm.nih.gov/pubmed/22291079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2011.39.2092
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