SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome

Aberrant expression of the secreted protein, acidic, cysteine-rich (osteonectin) (SPARC) gene, which encodes a matricellular protein that participates in normal tissue remodeling, is associated with a variety of diseases including cancer, but the contribution of SPARC to malignant growth remains con...

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Bibliografische gegevens
Hoofdauteurs: Alachkar, Houda, Santhanam, Ramasamy, Maharry, Kati, Metzeler, Klaus H., Huang, Xiaomeng, Kohlschmidt, Jessica, Mendler, Jason H., Benito, Juliana M., Hickey, Christopher, Neviani, Paolo, Dorrance, Adrienne M., Anghelina, Mirela, Khalife, Jihane, Tarighat, Somayeh S., Volinia, Stefano, Whitman, Susan P., Paschka, Peter, Hoellerbauer, Pia, Wu, Yue-Zhong, Han, Lina, Bolon, Brad N., Blum, William, Mrózek, Krzysztof, Carroll, Andrew J., Perrotti, Danilo, Andreeff, Michael, Caligiuri, Michael A., Konopleva, Marina, Garzon, Ramiro, Bloomfield, Clara D., Marcucci, Guido
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2014
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973087/
https://ncbi.nlm.nih.gov/pubmed/24590286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70921
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