A comparative study on the physicochemical and biological stability of IgG(1) and monoclonal antibodies during spray drying process

BACKGROUND: The main concern in formulation of antibodies is the intrinsic instability of these labile compounds. To evaluate the physicochemical stability of antibody in dry powder formulations, physical stability of IgG(1) and a monoclonal antibody (trastuzumab) during the spray drying process was...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ramezani, Vahid, Vatanara, Alireza, Najafabadi, Abdolhossein Rouholamini, Shokrgozar, Mohammad Ali, Khabiri, Alireza, Seyedabadi, Mohammad
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972992/
https://ncbi.nlm.nih.gov/pubmed/24641877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2008-2231-22-31
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