Clarithromycin Dissolution Enhancement by Preparation of Aqueous Nanosuspensions Using Sonoprecipitation Technique

Clarithromycin (CLM) is a member of macrolide family with broad spectrum antibiotic activity. It is practically insoluble in water and its poor solubility is pH dependent. In this study, series of nanosuspensions containing CLM and stabilizer such as HPMC, NaCMC, polysorbate 80, poloxamer 188 and po...

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Detalhes bibliográficos
Main Authors: Esfandi, Es ׳hagh, Ramezani, Vahid, Vatanara, Alireza, Rouholamini Najafabadi, Abdolhossein, Hadipour Moghaddam, Seyyed Pouya
Formato: Artigo
Idioma:Inglês
Publicado em: Shaheed Beheshti University of Medical Sciences 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177641/
https://ncbi.nlm.nih.gov/pubmed/25276181
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