A comparative study on the physicochemical and biological stability of IgG(1) and monoclonal antibodies during spray drying process

BACKGROUND: The main concern in formulation of antibodies is the intrinsic instability of these labile compounds. To evaluate the physicochemical stability of antibody in dry powder formulations, physical stability of IgG(1) and a monoclonal antibody (trastuzumab) during the spray drying process was...

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Main Authors: Ramezani, Vahid, Vatanara, Alireza, Najafabadi, Abdolhossein Rouholamini, Shokrgozar, Mohammad Ali, Khabiri, Alireza, Seyedabadi, Mohammad
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972992/
https://ncbi.nlm.nih.gov/pubmed/24641877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2008-2231-22-31
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