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Optimization and characterization of spray-dried IgG formulations: a design of experiment approach

BACKGROUND: The purpose of the present study is to optimize a spray-dried formulation as a model antibody regarding stability and aerodynamic property for further aerosol therapy of this group of macromolecules. METHOD: A three-factor, three-level, Box-Behnken design was employed milligrams of Cyste...

詳細記述

保存先:
書誌詳細
出版年:Daru
主要な著者: Faghihi, Homa, Najafabadi, Abdolhosein Rouholamini, Vatanara, Alireza
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678550/
https://ncbi.nlm.nih.gov/pubmed/29065930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40199-017-0187-8
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