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Optimization and characterization of spray-dried IgG formulations: a design of experiment approach
BACKGROUND: The purpose of the present study is to optimize a spray-dried formulation as a model antibody regarding stability and aerodynamic property for further aerosol therapy of this group of macromolecules. METHOD: A three-factor, three-level, Box-Behnken design was employed milligrams of Cyste...
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| 出版年: | Daru |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5678550/ https://ncbi.nlm.nih.gov/pubmed/29065930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40199-017-0187-8 |
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