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A comparative study on the physicochemical and biological stability of IgG(1) and monoclonal antibodies during spray drying process
BACKGROUND: The main concern in formulation of antibodies is the intrinsic instability of these labile compounds. To evaluate the physicochemical stability of antibody in dry powder formulations, physical stability of IgG(1) and a monoclonal antibody (trastuzumab) during the spray drying process was...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972992/ https://ncbi.nlm.nih.gov/pubmed/24641877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2008-2231-22-31 |
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