Innate Immune Protection against Infectious Diseases by Pulmonary Administration of a Phospholipid-Conjugated TLR7 Ligand

Pulmonary administration of Toll-like receptor (TLR) ligands protects hosts from inhaled pathogens. However, systemic side effects induced by TLR stimulation limit clinical development. Here, a small-molecule TLR7 ligand conjugated with phospholipid, 1V270 (also designated TMX201), was tested for in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Wu, Christina C.N., Crain, Brian, Yao, Shiyin, Sabet, Mojgan, Lao, Fitzgerald S., Tawatao, Rommel I., Chan, Michael, Smee, Donald F., Julander, Justin G., Cottam, Howard B., Guiney, Donald G., Corr, Maripat, Carson, Dennis A., Hayashi, Tomoko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: S. Karger AG 2014
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972367/
https://ncbi.nlm.nih.gov/pubmed/24192551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000355217
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