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Additive melanoma suppression with intralesional phospholipid conjugated TLR7 agonists and systemic IL-2

OBJECTIVE: There remains a compelling need for the development of treatments for unresectable melanoma. Agents that stimulate the innate immune response could provide advantages for cell based therapies. However there are conflicting reports concerning whether Toll-like receptor (TLR) signaling cont...

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Autores principales: Hayashi, Tomoko, Chan, Michael, Norton, John T., Wu, Christina C.N., Yao, Shiyin, Cottam, Howard B., Tawatao, Rommel I., Corr, Maripat, Carson, Dennis A, Daniels, Gregory A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057341/
https://ncbi.nlm.nih.gov/pubmed/21030882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0b013e328340ce6c
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