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P300 acetyltransferase regulates androgen receptor degradation and PTEN-deficient prostate tumorigenesis
Overexpression of the histone acetyltransferase p300 is implicated in the proliferation and progression of prostate cancer (PCa), but evidence of a causal role is lacking. In this study, we provide genetic evidence that this generic transcriptional co-activator functions as a positive modifier of pr...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3971883/ https://ncbi.nlm.nih.gov/pubmed/24480624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2485 |
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