P300 acetyltransferase regulates androgen receptor degradation and PTEN-deficient prostate tumorigenesis

Overexpression of the histone acetyltransferase p300 is implicated in the proliferation and progression of prostate cancer (PCa), but evidence of a causal role is lacking. In this study, we provide genetic evidence that this generic transcriptional co-activator functions as a positive modifier of pr...

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Autores principales: Zhong, Jian, Ding, Liya, Bohrer, Laura R., Pan, Yunqian, Liu, Ping, Zhang, Jun, Sebo, Thomas J., Karnes, R. Jeffrey, Tindall, Donald J., van Deursen, Jan, Huang, Haojie
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971883/
https://ncbi.nlm.nih.gov/pubmed/24480624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2485
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