CBP loss cooperates with PTEN haploinsufficiency to drive prostate cancer: implications for epigenetic therapy

Despite the high incidence and mortality of prostate cancer, the etiology of this disease is not fully understood. In this study, we develop functional evidence for CBP and PTEN interaction in prostate cancer based on findings of their correlate expression in the human disease. Cbp(pc−/−);Pten(pc+/−...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ding, Liya, Chen, Shuai, Liu, Ping, Pan, Yunqian, Zhong, Jian, Regan, Kevin M., Wang, Liguo, Yu, Chunrong, Rizzardi, Tony, Cheng, Liang, Zhang, Jun, Schmechel, Stephen C., Cheville, John C., van Deursen, Jan, Tindall, Donald J., Huang, Haojie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975662/
https://ncbi.nlm.nih.gov/pubmed/24491799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1659
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