CBP loss cooperates with PTEN haploinsufficiency to drive prostate cancer: implications for epigenetic therapy

Despite the high incidence and mortality of prostate cancer, the etiology of this disease is not fully understood. In this study, we develop functional evidence for CBP and PTEN interaction in prostate cancer based on findings of their correlate expression in the human disease. Cbp(pc−/−);Pten(pc+/−...

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Detalhes bibliográficos
Main Authors: Ding, Liya, Chen, Shuai, Liu, Ping, Pan, Yunqian, Zhong, Jian, Regan, Kevin M., Wang, Liguo, Yu, Chunrong, Rizzardi, Tony, Cheng, Liang, Zhang, Jun, Schmechel, Stephen C., Cheville, John C., van Deursen, Jan, Tindall, Donald J., Huang, Haojie
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975662/
https://ncbi.nlm.nih.gov/pubmed/24491799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1659
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