RUNX2 overexpression and PTEN haploinsufficiency cooperate to promote CXCR7 expression and cellular trafficking, AKT hyperactivation and prostate tumorigenesis

Rationale: The overall success rate of prostate cancer (PCa) diagnosis and therapy has been improved over the years. However, genomic and phenotypic heterogeneity remains a major challenge for effective detection and treatment of PCa. Efforts to better classify PCa into functional subtypes and eluci...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Bai, Yang, Yang, Yinhui, Yan, Yuqian, Zhong, Jian, Blee, Alexandra M., Pan, Yunqian, Ma, Tao, Karnes, R. Jeffrey, Jimenez, Rafael, Xu, Wanhai, Huang, Haojie
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587168/
https://ncbi.nlm.nih.gov/pubmed/31281490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.33292
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