RUNX2 overexpression and PTEN haploinsufficiency cooperate to promote CXCR7 expression and cellular trafficking, AKT hyperactivation and prostate tumorigenesis

Rationale: The overall success rate of prostate cancer (PCa) diagnosis and therapy has been improved over the years. However, genomic and phenotypic heterogeneity remains a major challenge for effective detection and treatment of PCa. Efforts to better classify PCa into functional subtypes and eluci...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Theranostics
Egile Nagusiak: Bai, Yang, Yang, Yinhui, Yan, Yuqian, Zhong, Jian, Blee, Alexandra M., Pan, Yunqian, Ma, Tao, Karnes, R. Jeffrey, Jimenez, Rafael, Xu, Wanhai, Huang, Haojie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Ivyspring International Publisher 2019
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587168/
https://ncbi.nlm.nih.gov/pubmed/31281490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.33292
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