P300 acetyltransferase regulates fatty acid synthase expression, lipid metabolism and prostate cancer growth

De novo fatty acid (FA) synthesis is required for prostate cancer (PCa) survival and progression. As a key enzyme for FA synthesis fatty acid synthase (FASN) is often overexpressed in human prostate cancers and its expression correlates with worse prognosis and poor survival. P300 is an acetyltransf...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gang, Xiaokun, Yang, Yinhui, Zhong, Jian, Jiang, Kui, Pan, Yunqian, Karnes, R. Jeffrey, Zhang, Jun, Xu, Wanhai, Wang, Guixia, Huang, Haojie
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924775/
https://ncbi.nlm.nih.gov/pubmed/26934656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7715
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