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Cysteine Pseudoprolines for Thiol Protection and Peptide Macrocyclization Enhancement in Fmoc-Based Solid-Phase Peptide Synthesis
[Image: see text] Contrary to other studies, here we describe cysteine (Cys) pseudoproline-containing peptides with short deprotection times in TFA. The deprotection times fell in the same range as other protecting groups commonly used in SPPS (e.g., 1–3 h). Moreover, when using Cys pseudoprolines a...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical Society
2014
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3971734/ https://ncbi.nlm.nih.gov/pubmed/24617568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol5004725 |
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