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Deprotection Reagents in Fmoc Solid Phase Peptide Synthesis: Moving Away from Piperidine?
The deprotection step is crucial in order to secure a good quality product in Fmoc solid phase peptide synthesis. 9-Fluorenylmethoxycarbonyl (Fmoc) removal is achieved by a two-step mechanism reaction favored by the use of cyclic secondary amines; however, the efficiency of the reaction could be aff...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6274427/ https://ncbi.nlm.nih.gov/pubmed/27854291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21111542 |
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