Efficient Synthesis of Peptides with 4-Methylpiperidine as Fmoc Removal Reagent by Solid Phase Synthesis

Solid phase peptide synthesis using the Fmoc/ t -Bu strategy (SPPS-Fmoc/tBu) is the most widely used methodology for obtaining synthetic peptides. In this paper, we evaluate the viability of using 4-methylpiperidine as a reagent for deprotection of the amino acid alpha amino group in SPPS-Fmoc/tBu....

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Библиографические подробности
Опубликовано в: :Journal of the Mexican Chemical Society
Главные авторы: Cristian Francisco Vergel Galeano, Zuly Jenny Rivera Monroy, Jaiver Eduardo Rosas Pérez, Javier Eduardo García Castañeda
Формат: Artigo
Язык:Inglês
Опубликовано: Sociedad Química de México 2014
Предметы:
Multidisciplinaria (Ciencias Naturales y Exactas)
piperidine
methylpiperidine
Synthetic Peptide
Fmoc removal reaction
Solid Phase Peptide Synthesis
Online-ссылка:https://www.redalyc.org/articulo.oa?id=47535733004
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