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Cysteine Pseudoprolines for Thiol Protection and Peptide Macrocyclization Enhancement in Fmoc-Based Solid-Phase Peptide Synthesis
[Image: see text] Contrary to other studies, here we describe cysteine (Cys) pseudoproline-containing peptides with short deprotection times in TFA. The deprotection times fell in the same range as other protecting groups commonly used in SPPS (e.g., 1–3 h). Moreover, when using Cys pseudoprolines a...
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| Główni autorzy: | , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Chemical Society
2014
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3971734/ https://ncbi.nlm.nih.gov/pubmed/24617568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol5004725 |
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