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Revisiting NO(2) as Protecting Group of Arginine in Solid-Phase Peptide Synthesis
The protection of side-chain arginine in solid-phase peptide synthesis requires attention since current protecting groups have several drawbacks. Herein, the NO(2) group, which is scarcely used, has been revisited. This work shows that it prevents the formation of δ-lactam, the most severe side-reac...
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| Publié dans: | Int J Mol Sci |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7352207/ https://ncbi.nlm.nih.gov/pubmed/32586051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124464 |
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