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Revisiting NO(2) as Protecting Group of Arginine in Solid-Phase Peptide Synthesis

The protection of side-chain arginine in solid-phase peptide synthesis requires attention since current protecting groups have several drawbacks. Herein, the NO(2) group, which is scarcely used, has been revisited. This work shows that it prevents the formation of δ-lactam, the most severe side-reac...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Alhassan, Mahama, Kumar, Ashish, Lopez, John, Albericio, Fernando, de la Torre, Beatriz G.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352207/
https://ncbi.nlm.nih.gov/pubmed/32586051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124464
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