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Revisiting NO(2) as Protecting Group of Arginine in Solid-Phase Peptide Synthesis

The protection of side-chain arginine in solid-phase peptide synthesis requires attention since current protecting groups have several drawbacks. Herein, the NO(2) group, which is scarcely used, has been revisited. This work shows that it prevents the formation of δ-lactam, the most severe side-reac...

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書目詳細資料
發表在:Int J Mol Sci
Main Authors: Alhassan, Mahama, Kumar, Ashish, Lopez, John, Albericio, Fernando, de la Torre, Beatriz G.
格式: Artigo
語言:Inglês
出版: MDPI 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352207/
https://ncbi.nlm.nih.gov/pubmed/32586051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124464
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