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DNA2 Resolves Expanding Flap in Mitochondrial Base Excision Repair

In a recent issue of Molecular Cell, Zheng et al. (2008) demonstrate that human DNA2, originally identified in yeast as a nuclear DNA replication and repair factor, functions exclusively in mammalian mitochondria in the recently discovered long-patch base excision repair pathway.

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Detalhes bibliográficos
Main Authors: Copeland, William C., Longley, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967838/
https://ncbi.nlm.nih.gov/pubmed/19026774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.11.007
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