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Distinct Conformations of a Putative Translocation Element in Poliovirus Polymerase

The mechanism whereby RNA is translocated by the single subunit viral RNA-dependent RNA polymerases is not yet understood. These enzymes lack homologs of the “O-helix” structures and associated fingers domain movements thought to be responsible for translocation in many DNA-templated polymerases. Th...

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Détails bibliographiques
Auteurs principaux: Sholders, Aaron J., Peersen, Olve B.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963463/
https://ncbi.nlm.nih.gov/pubmed/24424421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.12.031
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