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T cells and their eons-old obsession with MHC

T cells bearing receptors made up of α and β chains (TCRs) usually react with peptides bound to major histocompatibility complex proteins (MHC). This bias could be imposed by positive selection, the phenomenon that selects thymocytes to mature into T cells only if the TCRs they bear react with low b...

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Detalhes bibliográficos
Main Authors: Yin, Lei, Scott-Browne, James, Kappler, John W., Gapin, Laurent, Marrack, Philippa
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963424/
https://ncbi.nlm.nih.gov/pubmed/23046122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12004
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