Evolutionarily conserved features contribute to αβ T cell receptor specificity

αβ T cell receptors (TCRs) bind specifically to foreign antigens presented by major histocompatibility complex proteins (MHC) or MHC-like molecules. Accumulating evidence indicates that the germline-encoded TCR segments have features that promote binding to MHC and MHC-like molecules, suggesting co-...

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Bibliografiska uppgifter
Huvudupphovsmän: Scott-Browne, James P., Crawford, Frances, Young, Mary H., Kappler, John W., Marrack, Philippa, Gapin, Laurent
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245739/
https://ncbi.nlm.nih.gov/pubmed/21962492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.09.005
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