Effect of Activated Charcoal on Apixaban Pharmacokinetics in Healthy Subjects

BACKGROUND: Activated charcoal is commonly used to manage overdose or accidental ingestion of medicines. This study evaluated the effect of activated charcoal on apixaban exposure in human subjects. METHODS: This was an open-label, three-treatment, three-period, randomized, crossover study of single...

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Главные авторы: Wang, Xiaoli, Mondal, Sabiha, Wang, Jessie, Tirucherai, Giridhar, Zhang, Donglu, Boyd, Rebecca A., Frost, Charles
Формат: Artigo
Язык:Inglês
Опубликовано: Springer International Publishing 2013
Предметы:
Original Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961628/
https://ncbi.nlm.nih.gov/pubmed/24277644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40256-013-0055-y
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