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Prostate Cancer Induced by Loss of Apc Is Restrained by TGFβ Signaling

Recent work with mouse models of prostate cancer (CaP) has shown that inactivation of TGFβ signaling in prostate epithelium can cooperate with deletion of the Pten tumor suppressor to drive locally aggressive cancer and metastatic disease. Here, we show that inactivating the TGFβ pathway by deleting...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bjerke, Glen A., Pietrzak, Karolina, Melhuish, Tiffany A., Frierson Jr., Henry F., Paschal, Bryce M., Wotton, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961420/
https://ncbi.nlm.nih.gov/pubmed/24651496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092800
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