The Protein Kinase C Super-family Member PKN is Regulated by mTOR and Influences Differentiation During Prostate Cancer Progression

BACKGROUND: Phosphoinositide-3 (PI-3) kinase signaling has a pervasive role in cancer. One of the key effectors of PI-3 kinase signaling is AKT, a kinase that promotes growth and survival in a variety of cancers. Genetically engineered mouse models of prostate cancer have shown that AKT signaling is...

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Publicado no:Prostate
Main Authors: Yang, Chun-Song, Melhuish, Tiffany A., Spencer, Adam, Ni, Li, Hao, Yi, Jividen, Kasey, Harris, Thurl, Snow, Chelsi, Frierson, Henry, Wotton, David, Paschal, Bryce M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669364/
https://ncbi.nlm.nih.gov/pubmed/28875501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23400
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