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Prostate Cancer Induced by Loss of Apc Is Restrained by TGFβ Signaling
Recent work with mouse models of prostate cancer (CaP) has shown that inactivation of TGFβ signaling in prostate epithelium can cooperate with deletion of the Pten tumor suppressor to drive locally aggressive cancer and metastatic disease. Here, we show that inactivating the TGFβ pathway by deleting...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3961420/ https://ncbi.nlm.nih.gov/pubmed/24651496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092800 |
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