Učitavanje...
Premature Senescence and Increased TGFβ Signaling in the Absence of Tgif1
Transforming growth factor β (TGFβ) signaling regulates cell cycle progression in several cell types, primarily by inducing a G1 cell cycle arrest. Tgif1 is a transcriptional corepressor that limits TGFβ responsive gene expression. Here we demonstrate that primary mouse embryo fibroblasts (MEFs) lac...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325954/ https://ncbi.nlm.nih.gov/pubmed/22514746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035460 |
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