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A frequent, GxxxG-mediated, transmembrane association motif is optimized for the formation of interhelical Cα–H hydrogen bonds

Carbon hydrogen bonds between Cα–H donors and carbonyl acceptors are frequently observed between transmembrane helices (Cα–H···O=C). Networks of these interactions occur often at helix−helix interfaces mediated by GxxxG and similar patterns. Cα–H hydrogen bonds have been hypothesized to be important...

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Détails bibliographiques
Auteurs principaux: Mueller, Benjamin K., Subramaniam, Sabareesh, Senes, Alessandro
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956187/
https://ncbi.nlm.nih.gov/pubmed/24569864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319944111
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