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GxxxG Motifs, Phenylalanine, and Cholesterol Guide the Self-Association of Transmembrane Domains of ErbB2 Receptors

GxxxG motifs are common in transmembrane domains of membrane proteins and are often introduced to artificial peptides to inhibit or promote association to stable structures. The transmembrane domain of ErbB2 presents two separate such motifs that are proposed to be connected to stability and activit...

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Bibliografische gegevens
Hoofdauteurs: Prakash, Anupam, Janosi, Lorant, Doxastakis, Manolis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192960/
https://ncbi.nlm.nih.gov/pubmed/22004749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.017
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