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GxxxG Motifs, Phenylalanine, and Cholesterol Guide the Self-Association of Transmembrane Domains of ErbB2 Receptors

GxxxG motifs are common in transmembrane domains of membrane proteins and are often introduced to artificial peptides to inhibit or promote association to stable structures. The transmembrane domain of ErbB2 presents two separate such motifs that are proposed to be connected to stability and activit...

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Détails bibliographiques
Auteurs principaux: Prakash, Anupam, Janosi, Lorant, Doxastakis, Manolis
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192960/
https://ncbi.nlm.nih.gov/pubmed/22004749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.017
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