Lanean...

GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Aβ42

Processing of the amyloid precursor protein (APP) by β- and γ-secretases leads to the generation of amyloid-β (Aβ) peptides with varying lengths. Particularly Aβ42 contributes to cytotoxicity and amyloid accumulation in Alzheimer's disease (AD). However, the precise molecular mechanism of Aβ42...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Munter, Lisa-Marie, Voigt, Philipp, Harmeier, Anja, Kaden, Daniela, Gottschalk, Kay E, Weise, Christoph, Pipkorn, Rüdiger, Schaefer, Michael, Langosch, Dieter, Multhaup, Gerd
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829382/
https://ncbi.nlm.nih.gov/pubmed/17332749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601616
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!