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A Transmembrane Domain and GxxxG Motifs within L2 Are Essential for Papillomavirus Infection

During cellular invasion, human papillomavirus type 16 (HPV16) must transfer its viral genome (vDNA) across the endosomal membrane prior to its accumulation at nuclear PML bodies for the establishment of infection. After cellular uptake, the capsid likely undergoes pH-dependent disassembly within th...

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Detalhes bibliográficos
Main Authors: Bronnimann, Matthew P., Chapman, Janice A., Park, Chad K., Campos, Samuel K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536380/
https://ncbi.nlm.nih.gov/pubmed/23097431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01539-12
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