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Combination of Cα–H Hydrogen Bonds and van der Waals Packing Modulates the Stability of GxxxG-Mediated Dimers in Membranes

[Image: see text] The GxxxG motif is frequently found at the dimerization interface of a transmembrane structural motif called GAS(right), which is characterized by a short interhelical distance and a right-handed crossing angle between the helices. In GAS(right) dimers, such as glycophorin A (GpA),...

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Publicat a:J Am Chem Soc
Autors principals: Anderson, Samantha M., Mueller, Benjamin K., Lange, Evan J., Senes, Alessandro
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2017
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927632/
https://ncbi.nlm.nih.gov/pubmed/29028318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b07505
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