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APOE modulates the effect of estrogen therapy on Aβ accumulation EFAD-Tg mice

The post-menopausal loss of estrogen is key in the increased incidence of Alzheimer’s disease (AD) in women. However, estrogen therapy (ET) clinical trials have produced conflicting results. The APOE gene of apolipoprotein E (apoE) likely modulates the effects of ET in AD. APOE4 is the greatest gene...

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Bibliographic Details
Main Authors: Kunzler, Jacqueline, Youmans, Katherine L., Yu, Chunjiang, LaDu, Mary Jo, Tai, Leon
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955876/
https://ncbi.nlm.nih.gov/pubmed/24368217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2013.12.032
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