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Synergistic effects of APOE and sex on the gut microbiome of young EFAD transgenic mice
BACKGROUND: Alzheimer’s disease (AD) is a fatal neurodegenerative disease. APOE4 is the greatest genetic risk factor for AD, increasing risk up to 15-fold compared to the common APOE3. Importantly, female (♀) APOE4 carriers have a greater risk for developing AD and an increased rate of cognitive dec...
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| 出版年: | Mol Neurodegener |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6923910/ https://ncbi.nlm.nih.gov/pubmed/31861986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-019-0352-2 |
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