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The role of APOE in transgenic mouse models of AD
Identified in 1993, APOE4 is the greatest genetic risk factor for Alzheimer’s disease (AD), increasing risk up to 15-fold compared to the common variant APOE3. Since the mid 1990’s, transgenic (Tg) mice have been developed to model AD pathology and progression, primarily via expression of the famili...
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| Publicado no: | Neurosci Lett |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6717006/ https://ncbi.nlm.nih.gov/pubmed/31150730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2019.134285 |
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