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The role of APOE in transgenic mouse models of AD
Identified in 1993, APOE4 is the greatest genetic risk factor for Alzheimer’s disease (AD), increasing risk up to 15-fold compared to the common variant APOE3. Since the mid 1990’s, transgenic (Tg) mice have been developed to model AD pathology and progression, primarily via expression of the famili...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Neurosci Lett |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6717006/ https://ncbi.nlm.nih.gov/pubmed/31150730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2019.134285 |
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