The role of APOE in transgenic mouse models of AD

Identified in 1993, APOE4 is the greatest genetic risk factor for Alzheimer’s disease (AD), increasing risk up to 15-fold compared to the common variant APOE3. Since the mid 1990’s, transgenic (Tg) mice have been developed to model AD pathology and progression, primarily via expression of the famili...

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Detaylı Bibliyografya
Yayımlandı:Neurosci Lett
Asıl Yazarlar: Balu, Deebika, Karstens, Aimee James, Loukenas, Efstathia, Weng, Juan Maldonado, York, Jason M, Valencia-Olvera, Ana Carolina, LaDu, Mary Jo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717006/
https://ncbi.nlm.nih.gov/pubmed/31150730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2019.134285
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