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APOE modulates the effect of estrogen therapy on Aβ accumulation EFAD-Tg mice

The post-menopausal loss of estrogen is key in the increased incidence of Alzheimer’s disease (AD) in women. However, estrogen therapy (ET) clinical trials have produced conflicting results. The APOE gene of apolipoprotein E (apoE) likely modulates the effects of ET in AD. APOE4 is the greatest gene...

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Autori principali: Kunzler, Jacqueline, Youmans, Katherine L., Yu, Chunjiang, LaDu, Mary Jo, Tai, Leon
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955876/
https://ncbi.nlm.nih.gov/pubmed/24368217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2013.12.032
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